Government of Canada invests in university research infrastructure

New biomarkers to detect dementia among innovative projects awarded
April 14, 2014

HAMILTON, April 14, 2014 — The first signs of Alzheimer’s disease in Canada’s aging population may be detected earlier using new biomarkers being developed by Jennifer Heisz, a neuroscientist at McMaster University. Heisz’s brain biomarkers are neural signals she will use to detect disease, or the risk of disease, early and help measure the progress of treatments.


 

Ed Holder, Minister of State (Science and Technology), speaking
to Jennifer Heisz, a neuroscientist at McMaster University
who received funding from the Canada Foundation for Innovation’s
John R. Evans Fund.
Photo credit: Ron Scheffler

Heisz’s Neurophysiology and Fitness Laboratory is one of 149 facilities at universities across the country to benefit from new federal investments through the Canada Foundation for Innovation’s (CFI) John R. Evans Leaders Fund.

Ed Holder, Minister of State (Science and Technology), today announced more than $30.4 million in funding for research infrastructure at 32 universities across the country. These funds will also go to institutions with researchers working in areas such as pharmacology, infectious disease and materials engineering. The support will provide recipients with advanced tools that will help them generate research breakthroughs, expand Canada’s innovation capacity and contribute to the country’s economic success.

The CFI’s John R. Evans Leaders Fund helps these academic institutions attract and retain some of the world’s most talented researchers in a variety of disciplines.

Quick facts

  • The Canada Foundation for Innovation is awarding $23.4 million for tools and infrastructure that allow leading researchers to continue expanding the frontiers of science, health, social sciences and humanities. An additional $7 million will be used to support the operational costs of this infrastructure.
  • Alzheimer’s is projected to affect at least 1.4 million Canadians within the next 30 years at a cost of $293 billion a year.
  • McMaster University is receiving more than $850,000 in support of six initiatives with the same kind of potential for social and economic benefit as Dr. Heisz’s innovative research relating to Alzheimer’s.

Quotes

“Canadian researchers need state-of-the-art tools in order to undertake world-class research. Our government believes significant investment in these tools is essential to making scientific breakthroughs, which improve the lives of Canadians and increases economic prosperity.”

Ed Holder
Minister of State (Science and Technology)

“Cutting-edge facilities found at universities across the country become hubs where communities of students, researchers and entrepreneurs inspire each other to innovate. Their collaborations are vital to enhance Canada’s position as a global leader in research and enterprise.”

Dr. Gilles Patry
President and CEO of the CFI

“Universities are at the heart of discovery and innovation in Canada. These investments in state-of-the-art research tools and infrastructure will equip university researchers to develop new ideas and knowledge, find new treatments to make Canadians healthier, and generate discoveries that will make businesses more competitive.”

Paul Davidson
President, Association of Universities and Colleges of Canada

“This funding provides our researchers with the tools they need to pursue emerging areas that will impact the health and welfare of Canadians.  Awards such as the John R. Evans Leaders Fund catalyze the university research enterprise by ensuring our students have hands-on experience with the latest equipment and techniques and improve our researchers’ ability to attract the best candidates to their research teams.”

Patrick Deane
President and Vice-Chancellor, McMaster University

“The decline of cognitive abilities among Canada’s aging population poses a great challenge to our healthcare system, society and economy. With the CFI’s support, my team will have the tools to monitor brain function in new ways that may eventually give clinicians the means they need, whether through exercise or lifestyle changes, to prevent the onset of dementia among their older patients.”

Dr. Jennifer Heisz
Assistant Professor, Department of Kinesiology, McMaster University

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For updates, follow us on Twitter @InnovationCA and tune in to our Youtube channel for videos about the difference CFI-funded researchers are making in Canada.

Associated links

John R. Evans Leaders Fund

The CFI Research Facilities Navigator – A new online directory of CFI-funded labs across the country that are available to collaborate with the private sector. Four McMaster labs are currently listed in the Navigator.

McMaster University

Jennifer Heisz

Cumulative totals, by province

- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Nova Scotia
- Ontario
- Québec
- Saskatchewan

John R. Evans Leaders Fund

Institution

Projects Approved

Carleton University

1

Dalhousie University

1

École Polytechnique de Montréal

1

Laurentian University / Université Laurentienne

1

McGill University

14

McMaster University

6

Memorial University of Newfoundland

4

Mount Allison University

2

Queen’s University

3

Saint Mary’s University

2

Simon Fraser University

2

Université Laval

5

Université de Montréal

16

Université de Sherbrooke

4

Université du Québec - Institut national de la recherche scientifique

2

Université du Québec à Montréal

12

Université du Québec à Trois-Rivières

2

Université du Québec en Outaouais

2

University of Alberta

8

University of British Columbia (The)

18

University of Calgary

5

University of Guelph

2

University of Manitoba

4

University of New Brunswick

1

University of Saskatchewan

5

University of Toronto

14

University of Victoria

2

University of Waterloo

3

University of Western Ontario (The)

1

Vancouver Island Unversity

2

Wilfrid Laurier University

3

York University

1

Total Institutions                    32

149

 

 
List of Approved Projects by Institution

Project Title

Maximum CFI contribution

Carleton University

Infrastructure for Functional Genomics

$157,600

1 project / projet

$157,600

Dalhousie University

Infrastructure for the Couple and Sexual Health Laboratory

$125,000

1 project / projet

$125,000

École Polytechnique de Montréal

Laboratory of Organic Bioelectronics

200 000 $

1 projet / project

200 000 $

Laurentian University / Université Laurentienne

Enhanced Characterization Infrastructure for Canada Research Chair in Polymer

Nanomaterials

$83,112

1 project / projet

$83,112

McGill University

Tools for Mapping and Manipulating Motivational Neural Circuits

150 000 $

Active Biological Mechanics

280 000 $

Neural Circuits Underlying Sensorimotor Behaviors

140 000 $

A Study of Music Mixing Techniques Performed in a Hybrid Environment

86 752 $

Le geste expert et son contrôle dans la percussion contemporaine

80 000 $

Infrastructure for Analysis of Extracellular Matrix Assembly and Mineralization

100 000 $

Structural and Molecular Dynamics of Conformational Diseases

334 914 $

Assembly and Function of Protein Modules in Regulated Intramembrane Proteolysis

89 865 $

Single Cell Genomics Infrastructure

400 000 $

System to Study the Mechanics of Single Molecules with High Spatial and Temporal Resolution

279 038 $

Laboratory for Studying Host-Virus Interactions in Hepatitis C Virus Infections

80 000 $

Protein Structure at Near-Atomic Resolution Using a Direct Detection Device

291 600 $

Language Modelling Laboratory

78 817 $

Digital Musical Instrument Performance Research and Rapid Prototyping Laboratory (PR2P)

366 158 $

14 projets / projects

2 757 144 $

McMaster University

Removal of Micro-Particles in Steel Processing

$80,000

Brain Health in Aging: Preventing Dementia Through Exercise and Developing

Biomarkers for Early Detection

$100,000

McMaster Decision Science Laboratory (McDSL)

$100,000

Causes of Inadequate Reading Comprehension in Young Adults

$146,416

PEDAL 2.0: Secure Data Linking to Quantify Impacts of Social Intervention

$200,000

Infrastructure for an Immunometabolism Laboratory

$228,301

6 projects / projets

$854,717

Memorial University of Newfoundland

Advanced Dynamic Cyclic Simple Shear Apparatus

$100,000

Acquisition of a Liquid Water Isotope Analyzer for Hydrological, Geochemical, Ecological, and Oceanographic Research

$48,684

Gas-Phase Sampling Instrumentation for Ocean-Atmosphere and Biosphere- Atmosphere Interactions

$99,991

Construction of an Electrophysiological Recording System

$75,118

4 projects / projets

$323,793

Mount Allison University

Structure/Function Quantitations for Phytoplankton

$81,662

Infrastructure Supporting Discovery and Characterization of Algal DMSP Metabolism

$98,022

2 projects / projets

$179,684

Queen’s University

Linking Current and Future Environment, Physiology, Behaviour, and Life History in Birds

$80,000

Immune Cell Contributions to Endometrial Health and Disease

$100,000

Engineering a Smart Microgrid Test Platform

$400,000

3 projects / projets

$580,000

Saint Mary’s University

Enhancing Capability for Paleofluid and Melt Analysis in Mineral Exploration with

Laser Raman Spectroscopy

$95,697

Spectroscopic Measurements of Marine Boundary Layer Composition and Evolution in an Urban Shipping Environment

$118,862

2 project / projet

$214,559

Simon Fraser University

Fuel Cell and Battery Research Facility

$120,000

Liquid Chromatography-Mass Spectrometry (LC-MS) System for Developing

Sensitive and Quantitative Proteomics Techniques

$300,000

2 projects / projets

$420,000

Université Laval

Acquisition of a Pre-Clinical Positron Emission Tomography (PET) Camera and a Radiosynthesis Unit

167 714 $

Advanced Biomedical Microsystems Integration Platform

157 491 $

Analyse des mécanismes moléculaires régulés par l'oxygène dans les cellules de l'oeil

127 871 $

Probing the Development and Plasticity of the Brain: From Synapses to Circuit Formation

329 974 $

Leading Edge Enivironmental Analyses to Maintain and Restore Productive Ecosystems

104 000 $

5 projets / projects

887 050 $

Université de Montréal

Multimodal Assessment of Spinal and Supraspinal Interactions Ensuring Balance Control in Humans

100 397 $

Human Adoptive Immunotherapy, from Discovery to Development and Clinical Implementation

209 101 $

Improving Continence Care for Older Canadian Women: Supporting Future Innovation in the State-of-the-Art Laboratory

97 864 $

Understanding the Causes of Aneuploidy in Oocytes and Embryos

120 000 $

Biochemical Mechanisms of Epigenetic Inheritance

149 170 $

Family Demography in Historical Quebec: A Biosocial Perspective

112 350 $

Combining Intra-Vital and Fluorescence Lifetime Imaging Microscopy to Study the Effects of the Tumor Environment on TILs

80 000 $

Physical Simulation of Brain Microvasculature for Study of fMRI Contrast Mechanisms

116 370 $

Platform of Formulation Based on Multifunctional Lipids

143 953 $

Deep Phenotyping of Platelets for Precision Medicine in Cardiovascular Disease

120 640 $

PREMMIUM: Integrated Research Platform on Mental Health and Sexually Transmitted Infections

393 127 $

CYP450 Expression and Activity Quantification Platform

115 000 $

Impact of Preterm Birth on Adult Health and Diseases: Mechanisms and Translational Studies from Cells to Humans

345 000 $

Discovery of Immunodominant Minor Histocompatibility Antigens

120 000 $

Establishment of an Advanced Laboratory Specialized in the Study of T-Cell Development and Modulation

81 001 $

Neuronal Adhesion Mechanisms that Control GABAergic Synapse Development

151 681 $

16 projets / projects

2 455 654 $

Université de Sherbrooke

Platform for Molecular and Chemical Studies of Interactions Between Plant Roots and Beneficial Bacteria

120 000 $

Optical Characterization Test Bench for Single Photon Detection Instrumentation

113 690 $

New Approach for Cooperative Human-Robot Tasks and Cooperative Multi-Robots Tasks

32 271 $

Combining Transcranial Magnetic Stimulation with Brain Imaging for Studying Brain Circuits

105 863 $

4 projets / projects

371 824 $

Université du Québec - Institut national de la recherche scientifique

Laboratory of Bio-Hybrid Materials (LBM)

221 786 $

Laboratory of Nanostructure-Assisted Spectroscopy and Nonlinear Optics (NASNO Lab)

242 280 $

2 projets / projects

464 066 $

Université du Québec à Montréal

Laboratoire d'analyse cristalline des matériaux fonctionnels

110 000 $

TEAM-lab (laboratoire « technologies et apprentissages mobiles »)

120 000 $

Laboratoire de biochimie analytique et environnementale des contaminants

107 296 $

Modélisation et observation de l'atmosphère

160 000 $

Infrastructure to Support Research on Biodiversity and Litter Decomposition in Canadian Forests

120 000 $

Enhancing GEOTOP's Capability for Environmental Isotope Studies

63 601 $

Infrastructure de recherche sur la recharge de l'eau souterraine (IRRES)

215 492 $

Acquisition of a High-Performance Cell Sorter for Innovative Studies in Biomedical Research

100 000 $

An Analytical Platform to Support a Canadian Lake Observatory Network

100 001 $

Infrastructure to Study the Effects of Gastrointestinal Peptides on Excessive Lipid Deposition in Organs and Tissues

100 000 $

Analysis of Emerging Halogenated Organic Contaminants in Wildlife

77 528 $

Improving the Quality of Water Resources Contaminated by Diffuse Pollution:  Innovative Chemical-Isotope Laboratory

215 492 $

12 projets / projects

1 489 410 $

Université du Québec à Trois-Rivières

Optimisation de la plasticité cérébrale par stimulation non-invasive du cerveau chez les traumatisés crâniens légers

48 574 $

Subcellular Analysis of Stress Response Using Confocal Laser Scanning

Microscopy

139 050 $

2 projets / projects

187 624 $

Université du Québec en Outaouais

Laboratoire de recherche épidémiologique sur la maltraitance (LAREM)

138 528 $

Monitoring and Adapting Forests under Global Change

183 601 $

2 projets / projects

322 129 $

University of Alberta

Establishment of a Pediatric Nervous System Cancer and Development Laboratory

$172,000

Measurement and Modelling of Three-Phase Relative Permeability and Residual Oil Saturation in a SAGD Process

$80,000

High Speed Camera System for Imaging the Mechanics of Impact

$60,000

An Integrated Experimental System for Structural Health Monitoring of Critical Civil Infrastructure

$80,000

Infrastructure for the Discovery of New Catalysts and Chemical Reactivity

$114,000

Development of Laser Processing Facility for Wear and Corrosion Protection Materials

$200,000

Infrastructure for cEOR Polymer Characterization and ASP Design Research

$80,000

Molecular Study of Host Microbial Interactions

$160,000

8 projects / projets

$946,000



University of British Columbia (The)

Applied Genomics and Metagenomics for Population and Public Health

$125,000

Comprehesive Placenta Processing Suite (CPPS)

$125,000

Laboratory Infrastructure: Social Health Lab

$124,971

Investigating the Role of Blood-Based Proteolytic Cascades in Health and Disease

$144,273

New Therapeutic Strategies for Stroke

$240,000

Centre for Environmental Assessment Research

$44,17

Elucidation of Driver Molecular Pathways in Human Leukemia

$75,000

The Molecular Basis of Oral and Cardiovascular Disease: Regulation by Platelet Signaling

$125,000

Optical Characterization of Advanced Engine Combustion Strategies

$122,003

Outcomes Research in Community Pharmacy Practice: Innovation Using eHealth

$38,463

Cardiomyocyte Imaging

$71,327

Novel Translational Approaches for Targeting Misfolded Proteins in Alzheimer's Disease

$118,439

Investigation of Cerebrovascular Function

$27,360

Personalized Genomic Medicine for Improved Paediatric Drug Safety and Effectiveness

$110,698

Understanding the Formation and Resistance of Endodontic Biofilm

$123,365

Infrastructure Support for the UBC Steroid Profiling Laboratory

$254,806

Infrastructure to Study and Improve Stem Cell Function in Tissue Regeneration

$275,000

Laboratory for Population Dynamics in Changing Environments

$124,261

18 projects / projets

$2,269,140

University of Calgary

Paediatric Brain Imaging for Breakthroughs in Child Brain Health

$165,002

Oncolytic Virus Therapy for Cancer

$392,937

INSET: INfrastructure for Sustainable Electrochemical Technology

$147,999

Multimodal Gait Laboratory for Small Animals

$102,800

Infrastructure for Microscale Tissue Engineering

$182,900

5 projects / projets

$991,638

University of Guelph

Centre for Workers' Health and Well-being (CWHW)

$124,933

New Tools for Automated and Non-Invasive Animal Welfare Assessment

$115,916

2 projects / projets

$240,849

University of Manitoba

Microwave Imaging Infrastructure

$398,365

Laboratory for Organometallic Catalysis and Solar Fuels Research

$160,000

Imaging and Analysis Platform to Study Brain Injury and Neurodegeneration

$319,586

Infrastructure for Fingerprinting Hydrocarbons in the Arctic Marine Environment

$159,537

4 projects / projets

$1,037,488

 

University of New Brunswick

Laboratory for Advanced Carbon Materials Research

$366,685

1 project / projet

$366,685

University of Saskatchewan

Q-PROOF: Quantitative Protein and RNA Facility to Study Entry to and Exit From Drug Resistant Cancers

$51,699

Versatile Pilot Scale Radio Frequency System for Food and Bioprocess Research

$60,869

Portable Gas Chromatography to Support Biogeochemical Investigations of Closure Technologies for Oil Sands Mines

$37,043

EEG Hyperscanning Laboratory (EHL) for the Cognitive and Clinical Neuroscience of Inter-Brain Coordination

$177,721

Live Cell Imaging Microscope for Research in Reproductive and Developmental Biology

$229,777

5 projects / projets

$557,109

University of Toronto

Molecular Pathology of Cardiovascular Disease: Understanding How Gene Expression Is Perturbed in Clinical Samples

$376,643

High Performance Muscle Metabolism Suite

$180,830

Computational Approaches to Causal and Social Learning in Children and Animals

$100,000

Biophysics and Evolutionary Dynamics Laboratory

$359,660

Establishing a Knowledge Translation Centre for Identifying Inhibitors of Protein- Protein Interactions

$399,999

Exceptional Preservation in the Fossil Record

$51,626

Optimizing Use of Human Milk for Preterm Infants

$50,000

Mechanisms of Anesthesia and Sleep

$89,732

Advancing Paediatric Surgical Techniques and Childhood Nutrition Research by Utilizing Isotope-Ratio Mass Spectrometry

$269,340

Towards an Integrated Picture of Sensory Learning in Neural Circuits

$150,000

Cannabinoid Drug Discovery

$192,762

From Fracture to Fluids to Combustion: Infrastructure to Understand the Implications of Hydraulic Fracturing

$250,000

Monitoring Cancer Therapy Using Magnetic Resonance Imaging

$375,866

Combining Brain Imaging and Genetics for Treatment Innovation in Mental Illness

$287,849

14 projects / projets

$3,134,307

University of Victoria

UVic Behavioral Neuroscience Centre

$300,000

Ferry Ocean Colour Observation Systems (FOCOS)

$97,500

2 projects / projets

$397,500

 

University of Waterloo

Infrastructure for Multisensory Laboratory

$70,000

Equipment for Studies of Hybrid Quantum Systems of Spins and Superconductors

$200,000

High-Performance Polymer Materials for Printed Electronics

$70,000

3 projects / projets

$340,000

University of Western Ontario (The)

Infrastructure for the Analysis of Global Change Impacts on Tree and Forest Function

$179,347

1 project / projet

$179,347

Vancouver Island University

Real-Time Mobile Mass Spectrometry Laboratory

$398,104

Rejuvenating Health and Well-being: Resource Management and Social-Ecological Interactions in Coastal Estuaries

$98,822

2 projects / projets

$496,926

Wilfrid Laurier University

Characterization of the Alternative Oxidase of Pathogenic Protists and Treatment of Human Disease

$59,999

Structure and Function of Carbohydrate-Active Enzymes

$114,296

Comparative Molecular Physiology Imaging Infrastructure (CoMPII)

$60,000

3 projects / projets

$234,295

York University

Infrastructure for a Nanomaterials Laboratory

$124,000

1 project / projet

$124,000

NOTE:
As part of this announcement, an additional $7,016,595 was awarded under the Infrastructure Operating Fund, a mechanism that assists institutions with the incremental operating and maintenance costs associated with the new infrastructure.